Author

M. F. Hagan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 8

Signature Assays, Organisms & Methods

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Approach:simulation· 5 Approach:statistical model· 4 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

F. Mohajerani· 4 shared A. Baskaran· 1 shared A. Bausch· 1 shared A. Gopinath· 1 shared A. Sciortino· 1 shared A. Zlotnick· 1 shared B. Tyukodi· 1 shared C. J. Schlicksup· 1 shared

Activity by Year

2018-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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4 shared papersBiophysics

F. Mohajerani

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8 papers

Recent·Most cited

Active membrane deformations of a minimal synthetic cell

A. Sciortino, H. Faizi, S. Uplap, L. Frechette, M. S. Peterson, P. Vlahovska, A. Baskaran, M. F. Hagan, A. Bausch

This study introduces a synthetic cell model with an active cytoskeleton that exhibits shape fluctuations and morphing abilities, revealing how active forces influence membrane deformation dynamics.

bioRxiv · Dec 18, 2023Biophysics

Self-Assembly Coupled to Liquid-Liquid Phase Separation

M. F. Hagan, F. Mohajerani

This study investigates how liquid-liquid phase separation affects reversible self-assembly, finding it can enhance assembly rates and robustness against kinetic traps.

bioRxiv · Oct 13, 2022 · PreprintBiophysics

Effect of Ionic Strength on the Assembly of Simian Vacuolating Virus Capsid Protein Around Poly(Styrene Sulfonate)

R. Asor, S. W. Singaram, Y. Levi-Kalisman, M. F. Hagan, U. Raviv

The paper investigates how ionic strength affects SV40-like VLP assembly using SAXS, cryo-TEM, and Brownian dynamics simulations, revealing structural changes with ionic strength variations.

bioRxiv · Feb 25, 2022Biophysics

Multiscale Modeling of Hepatitis B Virus Capsid Assembly and its Dimorphism

F. Mohajerani, B. Tyukodi, C. J. Schlicksup, J. A. Hadden-Perilla, A. Zlotnick, M. F. Hagan

This study uses computational models to simulate HBV capsid assembly and identifies factors controlling its dimorphism.

bioRxiv · Feb 23, 2022Biophysics

Microcompartment assembly around multicomponent fluid cargoes

L. Tsidilkovski, F. Mohajerani, M. F. Hagan

This paper uses simulations to study how protein shells assemble around multicomponent fluid cargoes, showing that interaction strengths affect encapsulation and organization.

bioRxiv · Feb 23, 2022Biophysics

Synchronized oscillations, metachronal waves, and jammed clusters in sterically interacting active filament arrays

R. Chelakkot, M. F. Hagan, L. Mahadevan, A. Gopinath

This study uses simulations to show that steric interactions and surface roughness in active filament arrays can generate synchronized oscillations, metachronal waves, and jammed clusters.

Soft Matter · Jan 1, 2021Peer-reviewedBiophysics

Mechanisms of scaffold-mediated microcompartment assembly and size-control

F. Mohajerani, E. Sayer, C. Neil, K. Inlow, M. F. Hagan

The paper develops a computational model to study how scaffold proteins influence the assembly and size control of protein shells around cargo molecules, with implications for synthetic biology and cellular organization.

bioRxiv · Oct 14, 2020Biophysics

Gaussian curvature and the budding kinetics of enveloped viruses

M. F. Hagan, R. Bruinsma, S. Dharmavaram, S. B. She, G. Lazaro

The paper explains that the stalling of enveloped virus budding is due to a geometrical energy barrier caused by curvature conflicts between the viral capsid and the neck region, which can be overcome by the ESCRT machinery.

bioRxiv · Oct 30, 2018Biophysics