A mathematical model for pancreatic cancer during intraepithelial neoplasia
J. Briones-Andrade, G. Ramirez-Santiago, J. R. Romero-Arias
The paper develops a multiscale mathematical model of pancreatic adenocarcinoma evolution, showing that inflammatory processes and the RAS oncogene drive cancer progression from PanIN 1 to PanIN 2.
bioRxiv · Mar 16, 2024Cancer Biology