AI-assisted Discovery of an Ethnicity-influenced Driver of Cell Transformation in Esophageal and Gastroesophageal Junction Adenocarcinomas
P. Ghosh, V. J. Campos, D. T. Vo, C. Guccione, V. Goheen-Holland, C. Tindle, G. S. Mazzini, Y. He, L. Alexandrov, S. M. Lippman, R. Gurski, S. Das, K. Curtius, R. Yadlapati, D. Sahoo
The paper uses AI to identify a racially influenced immune driver of esophageal and gastroesophageal junction adenocarcinomas, showing its absence in African Americans and association with neutrophil processes and genetic variants.
bioRxiv · Jan 30, 2022Cancer Biology