A spatial multi-scale fluorescence microscopy toolbox discloses entry checkpoints of SARS-CoV-2 variants in Vero E6 cells
B. Storti, P. Quaranta, C. Di Primio, N. Clementi, N. Mancini, E. Criscuolo, P. G. Spezia, V. Carnicelli, G. Lottini, E. Paolini, G. Freer, M. Lai, M. Costa, F. Beltram, A. Diaspro, , R. Bizzarri
The paper uses multi-scale fluorescence microscopy to study SARS-CoV-2 variant entry into Vero E6 cells, finding B.1.1.7 enters faster than its ancestor due to the N501Y mutation.
bioRxiv · Mar 31, 2021Biophysics