Analysis and design of disordered polypeptides with optimized sequence patterning properties
Arjun Singh, Ali Ukperaj, Gabriel F. Porto, Gregory L. Dignon
This paper introduces a normalized sequence patterning framework for intrinsically disordered proteins and a design algorithm to generate sequences with desired phase separation properties.
PLoS Computational Biology · Jul 8, 2026Peer-reviewedBiophysics