Arjun Singh

This study investigates how sequence design parameters influence phase separation and mixing behavior of intrinsically disordered proteins (IDPs) when mixed.

This paper introduces a normalized sequence patterning framework for intrinsically disordered proteins and a design algorithm to generate sequences with desired phase separation properties.

This study shows phosphorylation of SARS-CoV-2 N protein toggles its condensate state between membrane-wetting and engulfment, revealing a regulatory mechanism for viral RNA replication and packaging.

This study demonstrates that large particles can be controlled and orthogonally partitioned into biomolecular condensates through strong particle-condensate interactions, using polymer nanoparticles with tailored surface chemistries.