γ-Secretase controls the specification of astrocytes from oligodendrocyte precursor cells via Stat3
Jinxing Hou, Huiru Bi, Gang Zou, Zhuoyang Ye, Jing Zhao, Yimin Hu, Jun Lan Lu, Guiquan Chen
This study shows that γ-secretase inhibition in OPCs reduces OL differentiation and increases astrocyte specification through Hes1-Stat3 regulation.
bioRxiv · Aug 28, 2019 · PreprintNeuroscience