Endothelin-1 from Tongue Glands Gates 1 Sodium Taste and Intake
Li-Tzu Chen, Xinyue Xia, Ernesto R Soto, Gary R Ostroff, Jin Zhang
This study shows that endothelin-1 from tongue glands modulates sodium taste and intake by inhibiting salt-sensing neurons, with effects reversed under sodium deficiency.
bioRxiv · Nov 2, 2026 · PreprintNeuroscience