Altered volume-regulated anion channel activity contributes to depression and anxiety-related molecular and behavioural phenotypes in zebrafish
Athira Ajith, Durai Shalu S, Gautam Mohapatra, Amal Kanti Bera
This study shows that disrupting VRAC function in zebrafish leads to depression- and anxiety-like behaviors and altered gene expression, while VRAC activation improves these phenotypes.
bioRxiv · Jul 27, 2026 · PreprintNeuroscience