Pharmacology & ToxicologybioRxivPreprint
Uncovering Non-Monotonic Antagonistic and Synergistic Combinations (UNMASC), a robust method with applications to T cell differentiation in vitro
Geneviève Bistodeau-Gagnon, Yale S. Michaels, Morgan Craig
The paper introduces UNMASC, a mathematical model to analyze non-monotonic cytokine interactions in T cell differentiation, showing synergistic and antagonistic effects in cytokine combinations.
DOI 10.1101/2025.09.07.674767