Improved detection of evolutionary selection highlights potential bias from different sequencing strategies in complex genomic-regions
Tristan J. Hayeck, Li Yang, Timothy L. Mosbruger, Jonathan P. Bradfield, Adam G. Gleason, George Damianos, Grace Tzun-Wen Shaw, Jamie L. Duke, Laura Kathleen Conlin, Tychele N. Turner, Marcelo Fernández-Viña, Mahdi Sarmady, Dimitri S. Monos
The paper develops a Bayesian method to detect balancing selection across different sequencing technologies and identifies novel genes under selection in complex genomic regions.
bioRxiv · Sep 28, 2021 · PreprintGenetics