In and out of replication stress: PCNA/RPA1-based dynamics of fork stalling and restart in the same cell
Teodora Dyankova-Danovska, Sonya Uzunova, Georgi Danovski, Rumen Stamatov, Petar-Bogomil Kanev, Aleksandar Atemin, Aneliya Ivanova, Radoslav Aleksandrov, Stoyno Stoynov
This study uses live-cell microscopy to analyze PCNA and RPA1 dynamics during replication fork stalling and restart in response to hydroxyurea, revealing distinct processes and the role of ATR in fork restart.
International Journal of Molecular Sciences · Jan 14, 2025Peer-reviewedMolecular Biology