Hunting for Helminths: short- and long-read shotgun metagenomics for parasite detection in faecal samples
Katie O’Brien, Ajay Elamaran, Mehmet Dayı, Georgia Keeling, William Nevin, Yuchen Liu, Mark Viney, Kieran Reynolds, Charmaine Bishop, Banchob Sripa, Menebere Woubshete, Pâmela Sachs Nique, Rhiannon Wright, Jane L. Younger, Vicky L. Hunt
This study validates shotgun metagenomics for detecting soil-transmitted helminths in faecal samples, finding mitochondrial sequence mapping as the most accurate method, with short-read sequencing outperforming long-read.
bioRxiv · Mar 10, 2026 · PreprintMolecular Biology