Overcoming oxygen impermeability in PDMS-free organ-on-a-chip microfluidics with nanoporous thermoplastic
Franziska Buck, Jeroen Bugter, Gerlinde Kruckenbaum, Insa Staecker, Marina Harzi, Antonina V. Lavrentieva, Thomas E. Winkler
This paper introduces nanoporous polycarbonate as a PDMS-free alternative for oxygen exchange in organ-on-a-chip systems, showing improved oxygen permeability and viability without compromising mechanical robustness.
bioRxiv · May 26, 2026 · PreprintBioengineering