Endogenous tau released from human ReNCell VM cultures by neuronal activity is phosphorylated at multiple sites
Ghadir Sindi, Sazan Ismael, Reaz Uddin, Kira G. Slepchenko, Robert A. Colvin, Daewoo Lee
This study shows that human ReNCell VM cells release tau under physiological conditions, with phosphorylation at specific sites being crucial for activity-dependent release.
bioRxiv · Jun 2, 2024 · PreprintNeuroscience