Effect of Cold Ischemia Time and Fixative preparation on Breast Cancer Biomarker Expression: Implications for Resource-Limited Settings
Clément Parfait Ndengue, Atangana Paul Jean Adrien, Gilbert Roger Ateba, Mandengue Samuel Honoré, Emile Télesphore Mboudou, Eboumbou Moukoko Caroline Else
This study evaluates the impact of fixative type and cold ischemia time on breast cancer biomarker preservation, finding non-buffered formaldehyde is nearly as effective as buffered formaldehyde, with minimal impact up to 2 hours of cold ischemia.
bioRxiv · Feb 9, 2026 · PreprintPathology