Single-cell transcriptome of developing inhibitory neurons reveals expanding and contracting modes of diversification.
Minhui Liu, Facundo Ferrero Restelli, Elia Micoli, Giulia Barbiera, Rani Moors, Evelien Nouboers, Malou Reverendo, Jessica Xinyun Du, Hannah Bertels, Dimitris Konstantopoulos, Keimpe Wierd, Aya Takeoka, Giordano Lippi, Lynette Lim
The paper develops a computational pipeline to enrich rare inhibitory neurons in scRNA-seq data, revealing three distinct modes of diversification in SST+ neurons during cortical development.
bioRxiv · Feb 19, 2025 · PreprintNeuroscience