Maintenance of active chromatin states by Hmgn1 and Hmgn2 is required for stem cell identity
Sylvia Garza-Manero, Abdulmajeed Abdulghani A. Sindi, Gokula Mohan, Ohoud Rehbini, Valentine Jeantet, Mariarca Bailo, Faeezah Abdul Latif, Maureen West, Ross Gurden, Lauren Finlayson, Silvija Svambaryte, Adam G. West, Katherine L. West
This study shows that Hmgn1 and Hmgn2 maintain active chromatin states necessary for stem cell identity by preventing spontaneous neuronal differentiation and preserving pluripotency markers.
Epigenetics & Chromatin · Dec 1, 2019Peer-reviewedMolecular Biology