Defining the T cell transcriptional landscape in pediatric liver transplant rejection at single cell resolution
Anna L. Peters, Erica A. K. DePasquale, Gousia Begum, Krishna M. Roskin, Michael Kotliar, Artem Barski, Nathan Salomonis, Tiffany Shi, Sarangarajan Ranganathan, E. Steve Woodle, David A. Hildeman
This study defines the transcriptional landscape of CD8+ T cells in pediatric liver transplant rejection using single-cell sequencing and identifies persistent CD8+ clones associated with graft failure.
American Journal of Transplantation · Aug 12, 2025Peer-reviewedImmunology