The polypharmacological profiles of xanomeline and N-desmethylxanomeline
Kensuke Sakamoto, Xi‐Ping Huang, Talia L. Albert, Paloma M. Knobloch, Grace K. Foland, Bryan L. Roth
This study investigates the polypharmacological profiles of xanomeline and its metabolite N-desmethylxanomeline, revealing their agonist and antagonist actions at multiple biogenic amine G protein-coupled receptors.
British Journal of Pharmacology · Apr 23, 2026Peer-reviewedNeuroscience