Real-world results from a Machine Learning-guided, phenotypic High-Throughput Screen for novel antibiotics
Paul Lukacs, Kevin C Hare, Shilpa George, Graham Hone, Gayatri Gollapudi, Lisa Wang Jarantow, J. Pellegrino, Alita A. Miller, Kurt S. Thorn
This study uses ML-guided HTS to discover novel antibiotics, achieving a doubled hit rate and reduced toxic hits against E. coli.
bioRxiv · Jun 22, 2026 · PreprintMicrobiology