Behavioral, Cardiovascular, and Neuroinflammatory Effects of 3-Aminobenzamide in a Rodent Model of Chronic Psychological Stress
Liza J. Wills, Hui Wang‐Heaton, Aaron James Polichnowski, Kristy L. Thomas, Benjamin E. Jewett, Seth M. Jewett, Grayson Aldridge, Gregory A. Ordway, Russell W. Brown, Michelle Chandley
This study investigates the effects of 3-aminobenzamide (3-AB), a PARP inhibitor, on chronic stress-induced behavioral, cardiovascular, and neuroinflammatory changes in rats, finding protective effects against behavioral deficits and neuroinflammation.
bioRxiv · Oct 6, 2026 · PreprintNeuroscience