Conditional deletion of human STN1 leads to telomere dysfunction and telomerase-dependent genome instability and proliferation defects
Jaclyn S. Holbrooks, Colin A. Loveless, S. Donte’ Reed, Grayson H. Duvall, Carlan V. Romney, Madison B. Kircher, Jason A. Stewart
This study shows that STN1 deletion causes telomere dysfunction, genome instability, and proliferation defects, which are telomerase-dependent.
bioRxiv · Aug 6, 2025 · PreprintCell Biology