Antinociceptive properties of an oral formulation of Δ9-tetrahydrocannabinol in aqueous 2-hydroxypropyl-β-cyclodextrin in female rats
Farshid Bagheri, María Scherma, Elisabetta Murru, Grazia Contena, Sebastiano Banni, Antonio Argiolas, Maria Rosaria Melis, Paola Fadda, Fabrizio Sanna
This study evaluates the antinociceptive effects of an oral THC/HPβCD formulation in female rats, showing efficacy at higher doses with some tolerance after chronic use.
bioRxiv · Aug 10, 2026 · PreprintPharmacology & Toxicology