Neuronal-specific methylome and hydroxymethylome analysis reveal replicated and novel loci associated with alcohol use disorder
Diego Andrade-Brito, Diana L. Núñez-Ríos, José Jaime Martínez‐Magaña, Sheila T. Nagamatsu, Gregory R. Rompala, Lea Zillich, Stephanie H. Witt, Shaunna L. Clark, María Claudia Lattig, PGC SUD Epigenetics Working Group, Janitza L. Montalvo‐Ortiz
This study identifies neuronal-specific DNA methylation and hydroxymethylation changes in the orbitofrontal cortex associated with alcohol use disorder, replicating prior findings and uncovering novel loci.
Frontiers in Genetics · Apr 3, 2024Peer-reviewedGenetic & Genomic Medicine