Stephanie H. Witt

This study shows estrogen receptor alpha in the amygdala influences alcohol craving in females through mouse models and human genetics.

This study identifies DNA methylation changes over time during antidepressant treatment in MDD, linking them to neuroplasticity and inflammation, and shows differences between responders and non-responders.

This study identifies cell type-specific DNA methylation associations with childhood ADHD symptoms using deconvolution and sequencing-based methylation data from peripheral and cord blood.

This study characterizes molecular changes in the ventral striatum of individuals with cocaine use disorder using multi-omics and single-cell approaches, identifying perturbations in metabolic pathways and cell-type-specific alterations.

The paper investigates whether 5-HTTLPR genotype differences in white matter microstructure explain risk-seeking behavior for losses, but finds no significant associations.

This study identifies neuronal-specific DNA methylation and hydroxymethylation changes in the orbitofrontal cortex associated with alcohol use disorder, replicating prior findings and uncovering novel loci.

This study uses LIS1-lissencephaly patient organoids to identify severity-dependent phenotypes and molecular mechanisms, and demonstrates that mTOR inhibitors can rescue disease-related changes.

This study examines DNA methylation at birth and its association with childhood cognitive skills, finding weak single CpG site associations and one region near DUSP22 linked to non-verbal cognition.

The paper examines how social interactions affect well-being before and during the pandemic, finding that personality, neurobiology, and genes moderate these effects.

The paper investigates genetic correlations between psychiatric disorders, personality traits, and SARS-CoV-2 susceptibility using GWAS data and individual-level polygenic risk scores.

This study identifies genetic loci associated with suicide attempts and shows shared genetic architecture with psychiatric disorders and non-psychiatric risk factors.

The paper identifies genetic associations with five personality dimensions and links them to psychiatric symptoms over time.

This paper identifies DNA methylation sites associated with aggression through a meta-analysis of epigenome-wide studies across different age groups and tissues.

The paper examines common genetic variants' contribution to bipolar disorder risk in multiplex families and finds higher polygenic risk scores in affected individuals compared to controls and unaffected family members.

The paper uses generative network models to identify spatial and topological mechanisms underlying altered structural brain connectivity in schizophrenia and its relatives.

This study conducts a trans-ancestral GWAS of alcohol dependence, identifying genetic variants and correlations with psychiatric disorders.