Modeling the dynamics of mouse iron body distribution: hepcidin is necessary but not sufficient
Jignesh H. Parmar, Grey Davis, Hope Shevchuk, Pedro Mendes
The paper develops a computational model of iron distribution in mice to test if hepcidin alone can regulate iron homeostasis under different dietary conditions, finding it insufficient in high iron diets.
BMC Systems Biology · May 18, 2017Peer-reviewedSystems Biology