Pedro Mendes

This study identifies CuiT as a key copper importer in Salmonella enterica, showing its role in copper homeostasis, gene regulation, and stress adaptation.

The paper develops a computational model of ferritin iron sequestration kinetics, validated against experimental data, showing FT concentration and saturation impact sequestration dynamics.

The paper identifies miRNA-transcription factor networks that mediate gene dosage compensation in aneuploid cancer cells, showing therapeutic potential through miRNA inhibition.

This paper develops a mathematical model of iron distribution in mice to simulate iron-related diseases and interventions.

The paper introduces a web service for automatic metabolic reaction balancing, enabling interoperability across systems biology tools by exposing the functionality as a RESTful API.

The paper develops a computational model of iron distribution in mice to test if hepcidin alone can regulate iron homeostasis under different dietary conditions, finding it insufficient in high iron diets.