DNA 5-methylcytosine regulates genome-wide formation of G-quadruplex structures
Kangkang Niu, Lijun Xiang, Xiaoyu Li, Jin Li, Yuanli Li, Chu Zhang, Junpeng Liu, Xiaojuan Zhang, Yuling Peng, Guanfeng Xu, Hui Xiang, Hao Wang, Qisheng Song, Qili Feng
This study shows that DNA 5-methylcytosine methylation reduces G-quadruplex formation, affecting gene transcription and linking epigenetic regulation to genome structure.
bioRxiv · Feb 16, 2023 · PreprintMolecular Biology