Author

Hao Wang

King's College LondonORCID 0000-0002-9971-1237Unclaimed ORCID profile · follow to get notified of new preprints

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Hao Wang12 papers · Altius Institute for Biomedical Sciences

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alice L. Fleckney· 1 shared Chu ZhangiD· 1 shared Doaa Boshra FaragiD· 1 shared Gayathri Nair SekhariD· 1 shared Guanfeng Xu· 1 shared Hui XiangiD· 1 shared Huzefa RupawalaiD· 1 shared Jin LiiD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Alice L. Fleckney

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2 papers

Recent·Most cited

DNA 5-methylcytosine regulates genome-wide formation of G-quadruplex structures

Kangkang Niu, Lijun Xiang, Xiaoyu Li, Jin Li, Yuanli Li, Chu Zhang, Junpeng Liu, Xiaojuan Zhang, Yuling Peng, Guanfeng Xu, Hui Xiang, Hao Wang, Qisheng Song, Qili Feng

This study shows that DNA 5-methylcytosine methylation reduces G-quadruplex formation, affecting gene transcription and linking epigenetic regulation to genome structure.

bioRxiv · Feb 16, 2023 · PreprintMolecular Biology

Region-specific blood-brain barrier transporter changes leads to increased sensitivity to amisulpride in Alzheimer’s disease

Gayathri Nair Sekhar, Alice L. Fleckney, Sevda Tomova Boyanova, Huzefa Rupawala, Rachel Lo, Hao Wang, Doaa Boshra Farag, Khondaker Miraz Rahman, Martin Broadstock, Suzanne Reeves, Sarah Ann Thomas

This study shows that changes in BBB transporters OCT1, PMAT, and MATE1 in Alzheimer’s disease increase sensitivity to amisulpride.

Fluids and Barriers of the CNS · Dec 1, 2019Peer-reviewedNeuroscience