Author

Guihua Duan

Central South University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:benchmarking· 1 Approach:diffusion model· 1 Assay:DNA methylation· 1 Organism:human· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Jianxin Wang· 2 shared Xiaoqing PengiD· 2 shared Hong‐Dong LiiD· 1 shared Honglin ZhuiD· 1 shared Kai Zheng· 1 shared Liqing DingiD· 1 shared Mengyun Yang· 1 shared Ruimin He· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBioinformatics

Jianxin Wang

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3 papers

Recent·Most cited

stEDGE enables edge-guided multiscale reconstruction of hierarchical spatial domains and transition interfaces in spatial transcriptomics

Yi He, Shuqi Chen, Liqing Ding, Ruimin He, Xiaoqing Peng, Guihua Duan, Honglin Zhu, Hong‐Dong Li, Shaokai Wang, Jianxin Wang

stEDGE reconstructs hierarchical spatial domains and transition interfaces in spatial transcriptomics by using edge-guided methods to capture multiscale organization beyond flat partitions.

bioRxiv · Sep 21, 2026 · PreprintBioinformatics

LRTM: Left-Right Transition Matrices for Molecular Interaction Prediction

Kai Zheng, Guihua Duan, Mengyun Yang, Wei Wu, Yao-Hang Li, Jianxin Wang

This paper introduces LRTM, a method for molecular interaction prediction using transition matrices, showing improved performance and cross-task potential.

bioRxiv · Feb 6, 2025 · PreprintBioinformatics

DMRIntTk: integrating different DMR sets based on density peak clustering

Wenjin Zhang, Wenlong Jie, Wanxin Cui, Guihua Duan, You Feng Zou, Xiaoqing Peng

DMRIntTk integrates DMR sets from different methods using density peak clustering to enhance methylation difference proportions and comprehensiveness.

bioRxiv · Jul 10, 2024 · PreprintBioinformatics