Glu-370 in the Large Subunit Influences the Substrate Binding, Allosteric, and Heat Stability Properties of Potato ADP-glucose Pyrophosphorylase
Ayse B Seferoglu, Seref Gul, Ugur M Dikbas, Kaan Koper, Ibrahim Baris, Mahmut Caliskan, Gul Cevahir, Ibrahim Kavakli
This study shows that changing Glu-370 to Gly in the large subunit of AGPase reduces substrate binding affinity, activation requirements, and heat stability.
bioRxiv · May 18, 2016Biochemistry