Effects of canagliflozin and irbesartan on renal fibrosis in Dahl salt-sensitive rats
Jianlong Zhai, Zhongli Wang, Tingting Zhang, Lili He, Sai Ma, Qingjuan Zuo, Guorui Zhang, Xinyu Wang, Yifang Guo
This study compares the antifibrotic effects of canagliflozin, irbesartan, and their combination in Dahl salt-sensitive rats on a high salt diet, showing improved renoprotection with combined therapy.
bioRxiv · Dec 27, 2022 · PreprintMolecular Biology