FibrilPaints for visualisation and ubiquitination of Huntingtin amyloid fibrils
Françoise A. Dekker, Emile van Weert, Guy Mayer, Tommaso Garfagnini, Júlia Aragonès Pedrola, Alfred C.O. Vertegaal, Assaf Friedler, Stefan Rüdiger
This paper introduces FibrilPaint peptides that selectively bind and track HttEx1Q44 amyloid fibrils, enabling monitoring of fibril growth and molecular targeting through ubiquitination.
bioRxiv · Feb 11, 2026 · PreprintBiochemistry