Author

Gwen W. Lau

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Organism:human· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Caroline Beasley· 4 shared Grace LianiD· 4 shared Shehzad Z. SheikhiD· 4 shared Sophie SilversteiniD· 4 shared Terrence S. FureyiD· 4 shared Bingfang Huan· 3 shared Matthew R. SchaneriD· 3 shared Muneera Rehana KapadiaiD· 3 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenomics

Caroline Beasley

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Transcriptome-wide Differential Expression and Splicing in Inflammatory Bowel Disease Patients

Shuying Han, Yu‐Chen Huang, Sophie Silverstein, Caroline Beasley, Muneera Rehana Kapadia, Gwen W. Lau, Grace Lian, Reza Rahbar, Timothy S. Sadiq, Matthew R. Schaner, Jonathan Stem, David Weaver, Bingfang Huan, Ariana LaCorte, Shehzad Z. Sheikh, Terrence S. Furey

The paper identifies differential expression and splicing in IBD patients, showing distinct molecular mechanisms in CD and UC.

bioRxiv · Oct 27, 2026 · PreprintGenomics

Reference-guided Genome Assembly of Long Non-coding RNA Transcripts reveals Target Genes Associated With Crohn's Disease

Meaghan M. Kennedy Ng, Sophie Silverstein, Nina C. Nishiyama, Caroline Beasley, Grace Lian, Bingfang Huan, Gwen W. Lau, David Andrew Weaver, Ayesh Awad, Matthew R. Schaner, Shehzad Z. Sheikh, Terrence S. Furey

The paper identifies differentially expressed lncRNAs in Crohn's disease using genome-guided RNA-seq and links them to nearby protein-coding genes involved in immune response and tissue regeneration.

Scientific Reports · May 25, 2026Peer-reviewedGenomics

Fatty Acid Oxidation Suppression Reprograms Fibroblasts in Fibrostenotic Crohns Disease

Jihad Jihad Aljabban, Ayesh Awad, Benjamin D. McMichael, Valerie Gartner, Viguna Thomas, Bingfang Huan, David Weaver, Grace Lian, Caroline Beasley, Gwen W. Lau, Sophie Silverstein, Muneera Rehana Kapadia, Anna C. Salvador, Florian Rieder, Jessica E. Thaxton, , Shehzad Z. Sheikh

The paper identifies impaired fatty acid oxidation in fibroblasts from fibrostenotic Crohn's disease patients and links it to intestinal fibrosis.

bioRxiv · May 10, 2026 · PreprintGenomics

eQTL in diseased colon tissue identifies novel target genes associated with IBD

Nina C. Nishiyama, Sophie Silverstein, Kimberly Darlington, Meaghan M. Kennedy Ng, Katelyn Clough, Mikaela J. Bauer, Caroline Beasley, Akshatha Bharadwaj, Rajee Ganesan, Muneera Rehana Kapadia, Gwen W. Lau, Grace Lian, Reza Rahbar, Timothy S. Sadiq, Matthew R. Schaner, , Terrence S. Furey

The paper identifies novel target genes associated with IBD by analyzing eQTL in diseased colon tissue and comparing them to non-IBD eQTL.

bioRxiv · Oct 14, 2024 · PreprintGenomics