Author

H. Alinejad-Rokny

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Approach:deep learning· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. Ebrahimi· 2 shared H. R. Rabiee· 2 shared J. Breen· 2 shared M. Bayati· 2 shared A. Dehzangi· 1 shared H. Dashti· 1 shared H. Hamidi· 1 shared M. Fateh· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersEvolutionary Biology

D. Ebrahimi

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Author profile →

4 papers

Recent·Most cited

A benchmarking of deep neural network models for cancer subtyping using single point mutations

P. Parhami, M. Fateh, M. Rezanavi, H. Alinejad-Rokny

This study benchmarks deep neural networks for cancer subtyping using somatic point mutations, finding CNN achieves the highest accuracy on a TCGA-derived dataset.

bioRxiv · Jul 24, 2022 · PreprintBioengineering

Somatic point mutations are enriched in long non-coding RNAs with possible regulatory function in breast cancer

N. Rezaie, M. Bayati, M. S. Tahaei, M. Hamidi, S. Khorasani, N. H. Lovell, J. Breen, H. R. Rabiee, H. Alinejad-Rokny

The paper identifies 929 non-coding RNAs significantly mutated in breast cancer and shows their enrichment in regulatory features and interactions with protein-coding gene promoters.

bioRxiv · Jul 19, 2021Cancer Biology

Signatures of Mutational Processes in Human DNA Evolution

H. Hamidi, H. Alinejad-Rokny, T. Coorens, R. Sanghvi, S. J. Lindsay, R. Rahbari, D. Ebrahimi

The paper identifies four mutational processes responsible for human genetic variations, with three active in all populations and one specific to mitochondrial DNA.

bioRxiv · Jan 9, 2021 · PreprintEvolutionary Biology

Integrative analysis of mutated genes and mutational processes reveals seven colorectal cancer subtypes

H. Dashti, A. Dehzangi, M. Bayati, J. Breen, N. Lovell, D. Ebrahimi, H. R. Rabiee, H. Alinejad-Rokny

This study identifies seven colorectal cancer subtypes by integrating mutated genes and mutational process motifs from ICGC data.

bioRxiv · May 18, 2020 · PreprintCancer Biology