Resistance of endothelial cells to SARS-CoV-2 infection in vitro
B. Ahmetaj-Shala, T. P. Peacock, L. Baillon, O. Swann, H. Gashaw, W. S. Barclay, J. A. Mitchell
This study shows that endothelial cells are resistant to SARS-CoV-2 infection due to low ACE2 and TMPRSS2 expression, suggesting vascular dysfunction in COVID-19 arises from inflammatory factors rather than direct viral infection.
bioRxiv · Nov 8, 2020 · PreprintImmunology