TET1 attenuates human pluripotency-related heterogeneities and enhances differentiation capabilities
M. Motono, K. Hiraki-Kamon, M. Kamon, H. Kiyosawa, Y. Kondo, H. Kato
This study shows that adding TET1 to hiPSCs improves their differentiation capabilities and reduces heterogeneity by correcting DNA methylation and gene expression deviations.
bioRxiv · Apr 29, 2022 · PreprintCell Biology