A comparison of the binding sites of antibodies and single-domain antibodies
G. L. Gordon, H. L. Capel, B. Guloglu, E. Richardson, R. L. Stafford, C. M. Deane
This study compares the binding sites of antibodies and single-domain antibodies, showing they target similar epitope sizes and shapes but differ in paratope interactions and framework residue importance.
bioRxiv · May 30, 2023Immunology