Author

H. N. Do

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

M. S. Wolfe· 2 shared Y. Miao· 2 shared A. Bhattarai· 1 shared J. Wang· 1 shared S. Bhattarai· 1 shared S. Devkota· 1 shared S. R. Malvankar· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 17 mutual co-author links

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2 shared papersBiophysics

M. S. Wolfe

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2 papers

Recent·Most cited

Molecular Dynamics Activation of γ-Secretase for Cleavage of Notch1 Substrate

H. N. Do, S. R. Malvankar, M. S. Wolfe, Y. Miao

This study uses molecular dynamics simulations and mass spectrometry to model how γ-secretase cleaves Notch1, revealing structural dynamics and substrate interactions.

bioRxiv · Sep 26, 2023Biophysics

Mechanism of Tripeptide Trimming by γ-Secretase

A. Bhattarai, S. Devkota, H. N. Do, J. Wang, S. Bhattarai, M. S. Wolfe, Y. Miao

This study investigates the mechanism of tripeptide trimming by γ-secretase using biochemical experiments and simulations, revealing structural changes required for the process and how mutations affect it.

bioRxiv · Aug 5, 2021 · PreprintBiochemistry