Digital spatial profiling of RNA in pancreatic neuroendocrine tumors highlights the distinct profile of alpha-SMA positive stroma and its impact on surrounding tumor cells
H. Niedra, R. Peculis, R. Saksis, S. Vilisova, A. Breiksa, A. Gerina-Berzina, J. Earl, I. Ruz-Caracuel, M. G. Rosas, V. Rovite
This study uses digital spatial profiling to analyze gene expression in pancreatic neuroendocrine tumor stroma and tumor cells, revealing distinct profiles and potential crosstalk mechanisms.
bioRxiv · Sep 5, 2023 · PreprintCancer Biology