HIV-1 Rev-RRE Functional Activity in Primary Isolates is Highly Dependent on Minimal Context-Dependent Changes in Rev
G. Dzhivhuho, J. Holsey, E. Honeycutt, H. O'Farrell, D. Rekosh, M.-L. A. Hammmarskjold, P. E. H. Jackson
This study shows that variations in the Rev protein of HIV-1 primary isolates affect Rev-RRE functional activity, with specific amino acid substitutions and sequence context playing key roles.
bioRxiv · Apr 29, 2022Microbiology