Author

H. R. Widlund

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

D. Yu· 1 shared J. Liang· 1 shared K. Wucherpfennig· 1 shared M. Jedrychowsk· 1 shared P. Puigserver· 1 shared S. P. Gygi· 1 shared T. D. Jackson· 1 shared T. Vitale· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

D. Yu

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1 paper

Recent·Most cited

Selective Mitochondrial Respiratory Complex I Subunit Deficiency Causes Tumor Immunogenicity

J. Liang, T. Vitale, X. Zhang, T. D. Jackson, D. Yu, M. Jedrychowsk, S. P. Gygi, H. R. Widlund, K. Wucherpfennig, P. Puigserver

This study shows that deleting specific mitochondrial Complex I subunits, Ndufs4 and Ndufs6, enhances tumor immunogenicity and sensitivity to immune checkpoint blockade in mouse melanoma models.

bioRxiv · Oct 2, 2023 · PreprintCancer Biology