Fexinidazole induced cytotoxicity is distinct from related anti-trypanosome nitroaromatic drugs
I. Rogers, K. Berg, H. Ramirez, G. Hovel-Miner
This study compares the cytotoxic effects of fexinidazole, nifurtimox, and benznidazole on Trypanosoma brucei, showing fexinidazole uniquely inhibits DNA synthesis while the others induce DNA damage.
bioRxiv · Oct 9, 2023 · PreprintMicrobiology