Combining computational biology and experimental knowledge to draw a structural profile of the active membrane-assembled NADPH oxidase complex
S. Z. Aimeur, B. A. Fas, X. Serfaty, H. Santuz, S. Sacquin-Mora, T. Bizouarn, A. Taly, L. BACIOU
The paper models the structure of the active NOX2 complex using AlphaFold2 and experimental data, revealing the role of disordered regions in subunit assembly.
bioRxiv · Feb 19, 2024 · PreprintBiochemistry