The immune checkpoint kick start: Optimization of neoadjuvant combination therapy using game theory
J. West, M. Robertson-Tessi, K. Luddy, D. S. Park, D. F. K. Williamson, C. Harmon, H. T. Khong, J. Brown, A. R. A. Anderson
The paper develops a mathematical model to optimize neoadjuvant combination therapy for ER+ breast cancer by balancing tumor burden and metastatic potential using game theory.
bioRxiv · Jun 18, 2018Cancer Biology