Conserved structural elements specialize ATAD1 as a membrane protein extraction machine
L. Wang, H. Toutkoushian, C. Y. Kokontis, P. Walter, V. Belyy
This study determines the cryo-EM structure of human ATAD1 with a peptide substrate, revealing conserved structural elements that enable its function in extracting mislocalized membrane proteins.
bioRxiv · Sep 24, 2021Biochemistry