Single-cell proteomics reveals proteome remodeling and cellular heterogeneity during NGF-induced PC12 neuronal differentiation
Arpa Ebrahimi, Shuxin Chi, Jun Yang, Phoebe Y. Lee, Prongbaramee K. Colling, Hailey Mendenhall, Zejing Wang, Chad Giusti, Leonard J. Foster, David A. Hendrix, Claudia S. Maier
The paper applies single-cell proteomics to study proteome changes during NGF-induced PC12 differentiation, revealing subpopulations not detected in bulk data.
ACS Chemical Neuroscience · Jul 28, 2026Peer-reviewedNeuroscience