Claudia S. Maier

The paper applies single-cell proteomics to study proteome changes during NGF-induced PC12 differentiation, revealing subpopulations not detected in bulk data.

GIRAFI improves sparse single-cell proteomics by imputing missing values and revealing cell states using graph-informed statistical learning, outperforming existing methods and recovering biological structure.

The paper introduces a cost-effective single-cell proteomics workflow and a data evaluation framework to improve data quality and biological interpretability.

This study identifies early synaptic and metabolic dysfunctions in 5xFAD mice before plaque formation, linking them to hippocampal vulnerability in Alzheimer's disease.

The paper investigates compound interactions in Centella asiatica using multi-omics analysis on mouse neurons, revealing both positive and negative effects on gene and metabolite profiles.

This study identifies gut microbiota-mediated metabolites that influence intestinal helminth infection in zebrafish, highlighting potential therapeutic targets.

This study shows that Centella asiatica extract improves age-related cognitive decline and anxiety in mice, but effects vary by sex, dose, and administration method.

This study shows that TXN reduces pro-inflammatory gut microbes and alleviates adipose tissue inflammation, improving metabolic syndrome in mice.

This study shows TXN, a xanthohumol derivative, reduces hepatic steatosis in mice by antagonizing PPARγ, similar to pioglitazone.