Brain endothelial PRMT5-ANGPTL4 axis regulates cerebellar inhibitory synaptogenesis and motor coordination
Jinjin Lu, Yizhe Zhang, Yijie Hao, Huimin Ning, Zizhao Fan, Shiqiang Hao, Yaxiong Cui, Yuying Han, Y.F. Cai, Wenjia Liu, Haiou Ao, Shunshun Xiu, Jun Wang, Xiao Yi Yang
This study identifies the endothelial PRMT5-ANGPTL4 axis as critical for cerebellar inhibitory synaptogenesis and motor coordination in mice.
bioRxiv · Nov 18, 2025 · PreprintNeuroscience